Case Control Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Sep 22, 2016; 6(3): 339-344
Published online Sep 22, 2016. doi: 10.5498/wjp.v6.i3.339
Chronic pelvic pain, psychiatric disorders and early emotional traumas: Results of a cross sectional case-control study
Flávia L Osório, Ana Carolina F Carvalho, Mariana F Donadon, André L Moreno, Omero Polli-Neto
Flávia L Osório, Ana Carolina F Carvalho, Mariana F Donadon, André L Moreno, Omero Polli-Neto, Medical School of Ribeirão Preto, São Paulo University, Ribeirão Preto 14048-900, Brazil
Author contributions: Osório FL and Poli-Neto O designed research; Carvalho ACF and Donadon MF collected material and clinical data from patients; Osório FL and Carvalho ACF analysed data; Osório FL, Poli-Neto and Moreno AL wrote the paper.
Supported by CNPq - National Counsel of Technological and Scientific Development, No. 471441/2012-0.
Institutional review board statement: The study was reviewed and approved by the Comitê de Ética em Pesquisa do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors state that they have no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Flávia L Osório, Professor, Medical School of Ribeirão Preto, São Paulo University, Avenida dos Bandeirantes 3900, Ribeirão Preto 14048-900, Brazil. flaliosorio@gmail.com
Telephone: +51-16-36022530 Fax: +51-16-36022703
Received: March 4, 2016
Peer-review started: March 8, 2016
First decision: April 20, 2016
Revised: July 26, 2016
Accepted: August 30, 2016
Article in press: August 31, 2016
Published online: September 22, 2016
Processing time: 194 Days and 17.1 Hours
Abstract
AIM

To compare the prevalence of psychiatric disorders and early emotional traumas between women with chronic pelvic pain (CPP) and healthy women.

METHODS

One hundred women in reproductive age, 50 of them had CPP (according to the criteria set by the International Association for Study of Pain), and 50 were considered healthy after the gynecological evaluation. The eligibility criteria were defined as follows: chronic or persistent pain perceived in the pelvis-related structures (digestive, urinary, genital, myofascial or neurological systems). Only women in reproductive age with acyclic pain for 6 mo, or more, were included in the present study. Menopause was the exclusion criterion. The participants were grouped according to age, school level and socio-economic status and were individually assessed through DSM-IV Structured Clinical Interview (SCID-I) and Early Trauma Inventory Self-report - short form (ETISR-SF Brazilian version). Descriptive statistics, group comparison tests and multivariate logistics regression were used in the data analysis.

RESULTS

The early emotional traumas are highly prevalent, but their prevalence did not differ between the two groups. The current Major Depressive Disorder was more prevalent in women with CPP. The CPP was associated with endometriosis in 48% of the women. There was no difference in the prevalence of disorders when endometriosis was taken into account (endometriosis vs other diseases: P > 0.29). The current Major Depressive Disorder and the Bipolar Disorder had greater occurrence likelihood in the group of women with CPP (ODDS = 5.25 and 9.0).

CONCLUSION

The data reinforce the link between mood disorders and CPP. The preview evidences about the association between CPP and early traumas tended not to be significant after a stronger methodological control was implemented.

Keywords: Pelvic pain; Psychiatric disorder; Early trauma; Emotional; Depression

Core tip: There is also evidence about the association between depressive and anxious symptoms and the presence of chronic pelvic pain (CPP). The weakest points in these data refer to the quality of the studies; as most of them are descriptive and assess symptoms, instead of confirming the disorder symptoms, which may affect the understanding of the link between conditions. The current study used “gold standard” psychiatric diagnostic instruments to assess the presence or absence of Axis I mental disorders. The results showed associations between mood disorders and CPP, but the association between CPP and early trauma tends not to be significant after increased methodological control.