Published online Sep 19, 2023. doi: 10.5498/wjp.v13.i9.675
Peer-review started: May 24, 2023
First decision: June 12, 2023
Revised: June 25, 2023
Accepted: August 2, 2023
Article in press: August 2, 2023
Published online: September 19, 2023
Spiritual wellbeing emphasizes optimistic and positive attitudes while self-regulating negative emotions when coping with stress. However, there have only been a few small studies of spiritual wellbeing of pancreatic ductal adenocarcinoma (PDAC) patients undergoing chemotherapy. The core factors influencing spiritual wellbeing in this clinical population are still unclear.
To identify factors influencing spiritual wellbeing among patients with PDAC receiving chemotherapy.
A total of 143 PDAC patients receiving chemotherapy were enrolled from January to December 2022. Patients completed general information questionnaires including: Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being 12 Item Scale (FACIT-Sp-12), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) and Zung’s Self-rating Anxiety Scale (SAS). Independent sample t-test, one-way analysis of variance, Pearson’s correlation analysis, and multiple linear regression analysis were adopted for statistical analyses. P < 0.05 (two-tailed) was considered statistically significant for all tests.
Total spiritual wellbeing (FACIT-Sp-12) score was 32.16 ± 10.06 points, while dimension sub-scores were 10.85 ± 3.76 for faith, 10.55 ± 3.42 for meaning, and 10.76 ± 4.00 for peace. Total spiritual wellbeing score was negatively correlated with SAS score for anxiety and with the symptom domain of EORTC QLC-C30. Conversely, spiritual wellbeing score was positively correlated with global health status and EORTC QLQ-C30 role functioning domain score. Multivariate regression analysis identified educational level, health insurance category, symptom domain, functional role domain, and global health status as significant independent factors influencing spiritual wellbeing among PDAC patients undergoing chemotherapy (R2 = 0.502, P < 0.05).
Individualized spiritual support is needed for PDAC patients. Health, daily functioning, emotional, cognitive, and social function status should be taken into account to promote implementation of spirituality in nursing practice.
Core Tip: Identifying the core factors influencing spiritual wellbeing of pancreatic ductal adenocarcinoma (PDAC) patients undergoing chemotherapy and formulating individualized spiritual care regimens can improve quality of life. However, there have only been a few small studies on spiritual wellbeing of PDAC patients undergoing chemotherapy. The core factors influencing spiritual wellbeing in this clinical population are still unclear. In this study, we analyzed factors influencing the spiritual wellbeing of PDAC patients undergoing chemotherapy, the newest study of PDAC patients undergoing chemotherapy in Mainland China.