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World J Hypertens. Feb 23, 2016; 6(1): 36-40
Published online Feb 23, 2016. doi: 10.5494/wjh.v6.i1.36
Place of baroreceptor activation therapy in the treatment of resistant hypertension
Gian Paolo Rossi, Matteo Azzolini
Gian Paolo Rossi, Matteo Azzolini, Clinica dell’Ipertensione Arteriosa, Department of Medicine-DIMED, University of Padua, 35126 Padua, Italy
Author contributions: Rossi GP wrote the paper; Azzolini M performed the collected the data.
Supported by FORICA (The Foundation for Advanced Research in Hypertension and Cardiovascular diseases); the University of Padua (to GPR); HORIZON 2020; and COST-ADMIRE.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Gian Paolo Rossi, MD, FACC, FAHA, Professor, Clinica dell’Ipertensione Arteriosa, Department of Medicine-DIMED, University of Padua, Via Giustiniani 2, 35126 Padova, Italy. gianpaolo.rossi@unipd.it
Telephone: +39-049-8212279 Fax: +39-049-8217873
Received: September 1, 2015
Peer-review started: September 8, 2015
First decision: September 29, 2015
Revised: October 7, 2015
Accepted: December 9, 2015
Article in press: December 10, 2015
Published online: February 23, 2016
Core Tip

Core tip: We herein describe the development of the therapeutic concept of baroreceptor stimulation for the treatment of drug-resistant hypertension. The ups and downs of this treatment strategy are discussed in the light of the results of the studies done in the last decade.