Flavonoids extract from Vitex negundo inhibit autophagy by targeting PI3K/AKT/mTOR/p70S6K/ULK signaling cascade in cancerous cells

Table 1 Flavonoids isolated from different parts of Vitex negundo

No.	Compound name (flavonoids)	Plant parts
1	5-Hydroxy-7,4′-dimethoxy flavone	Leave
2	5,7-Dihydroxy-6,4′-dimethoxy flavone	Leave
3	Luteolin	Leaves
4	Luteolin-7-O-β-D-glucoside	Leave
5	7,8-Dimethyl herbacetin-3-rhamnoside	Leave
6	Vitegnoside	Leaves
7	Iso-orientin	Leaves
8	Chrysoplenetin	Seeds
9	Chrysosplenol D	Seeds
10	4′,5-Dihydroxy-3,6,7-trimethoxyflavone	Seeds
11	5,3′-Hydroxy-6,7,4′-trimethoxy flavone	Leave
12	5,7,3′-Trihydroxy-6,8,4′-trimethoxyflavone	Leaves
13	Acerosin-5-O-glucoside	Leaves
14	Corymbosin	Leave, twigs
15	15 5-Hydroxy-6,7,8,3′,4′-pentamethoxyflavone	Leave, twigs
16	5,6,7,8,3′,4′,5′-Heptamethoxyflavone	Leave
17	Casticin	Seeds
18	5,3′-Hydroxy-7,8,4′-trimethoxyflavone	Stem bark
19	3,6,7,3′,4′-Pentamethoxyflavone-5-O-glucopyransylrhamnoside	Stem bark
20	5-Hydroxy-6,7,8,4′-tetramethoxyflavone	Leave, twigs
21	Vitexin cafeate	Stem bark
23	Vitexicarpin	Leaves
24	Vitexin cafeate	Stem bark
25	3,6,7,3′,4′-Pentamethoxy-5-O-glucopyranosyl-rhamnoside	Stem bark
26	4′-O-methylmyricetin-3-O-[4′′-O-β-D-galactosyl]-β-D-galactopyranoside	Stem bark
27	3,4,5,7,3′,4′,5′-Hexahydroxy-6,8-dimethoxyflavone	Leave, twigs
28	4,5-Dihydroxy-3′,4′-dimethoxyflavone-6-O-rhamnoglucoside	Leave, twigs
29	5,7-Dihydroxychromone Seeds	Seeds