Published online Mar 28, 2015. doi: 10.5412/wjsp.v5.i1.167
Peer-review started: August 6, 2014
First decision: August 28, 2014
Revised: September 13, 2014
Accepted: February 9, 2015
Article in press: February 11, 2015
Published online: March 28, 2015
Core tip: Prophylactic oophorectomy is a potentially attractive additional procedure that can be performed at the time of primary colorectal resection, to reduce the risk of ovarian metastasis and de novo ovarian malignancy later in a female patient’s clinical course. A systematic review and meta-analysis of the available literature reveals that, though this procedure can be performed with little additional morbidity or mortality risk at the time of surgery, it confers no long term survival benefit, and carries a significant side effect profile.