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World J Immunol. Nov 27, 2014; 4(3): 185-193
Published online Nov 27, 2014. doi: 10.5411/wji.v4.i3.185
Published online Nov 27, 2014. doi: 10.5411/wji.v4.i3.185
Modulation of monocyte subsets in infectious diseases
Mignane B Ka, Daniel Olive, Inserm Unité Mixte de Recherche (UMR) 1068, Centre de Recherche en Cancérologie de Marseille, 13009 Marseille, France
Mignane B Ka, Jean-Louis Mege, Department of Immunology and Infectious Diseases, Aix Marseille University, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, 13005 Marseille, France
Author contributions: Ka MB and Mege JL wrote the paper; Mege JL and Olive D corrected it.
Correspondence to: Jean-Louis Mege, Professor, Department of Immunology and Infectious Diseases, URMITE, Faculté de Médecine, 27 BD Jean Moulin, 13005 Marseille,France. jean-louis.mege@univ-amu.fr
Telephone: +33-4-91324970 Fax: +33-4-91324306
Received: June 1, 2014
Revised: July 10, 2014
Accepted: August 27, 2014
Published online: November 27, 2014
Revised: July 10, 2014
Accepted: August 27, 2014
Published online: November 27, 2014
Core Tip
Core tip: In this review of the literature we show that monocyte subsets are differently affected during viral, bacterial, parasitic and fungal infections. We observe that the CD16+ compartment (intermediate and non-classical monocytes) is typically increased in the majority of infectious diseases. The measurement of monocyte subsets would be useful in better understanding of the role of monocyte activation in the pathophysiology of infectious diseases.