Published online Feb 8, 2014. doi: 10.5409/wjcp.v3.i1.6
Revised: January 7, 2014
Accepted: January 17, 2014
Published online: February 8, 2014
Core tip: Childhood obesity is growing at an alarming rate and is concomitant with an increasing prevalence of oxidative stress. The association between obesity and oxidative stress is illustrated in the present study that showed that obese children with body mass index greater than 35 kg/m2 had higher oxidative products, e.g., malondialdehyde, advanced oxidation protein products and oxidized low-density lipoprotein concentrations with lower antioxidants, e.g., superoxide dismutase, catalase, glutathione peroxidase (GSH-Px) and glutathione reductase, and GSH. Therefore, the early recognition of these changes in oxidant status in children is important for preventing the long-term complications of obesity and targeting individual subjects who are particularly at risk. In addition, improving the oxidant status in overweight and obese children may reduce obesity-related comorbidities in adulthood.