Published online Sep 9, 2023. doi: 10.5409/wjcp.v12.i4.162
Peer-review started: July 9, 2023
First decision: July 19, 2023
Revised: August 9, 2023
Accepted: August 23, 2023
Article in press: August 23, 2023
Published online: September 9, 2023
Investigating gastrointestinal (GI) motility disorders relies on diagnostic tools to assess muscular contractions, peristalsis propagation and the integrity and coordination of various sphincters. Manometries are the gold standard to study the GI motor function but it is increasingly acknowledged that manometries do not provide a complete picture in relation to sphincters competencies and muscle fibrosis. Endolumenal functional lumen imaging probe (EndoFLIP) an emerging technology, uses impedance planimetry to measure hollow organs cross sectional area, distensibility and compliance. It has been successfully used as a complementary tool in the assessment of the upper and lower oesophageal sphincters, oesophageal body, the pylorus and the anal canal. In this article, we aim to review the uses of EndoFLIP as a tool to investigate GI motility disorders with a special focus on paediatric practice. The majority of EndoFLIP studies were conducted in adult patients but the uptake of the technology in paediatrics is increasing. EndoFLIP can provide a useful complementary data to the existing GI motility investigation in both children and adults.
Core Tip: Manometries are commonly used to investigate gastrointestinal (GI) motility disorders albeit with acknowledged limitation to their diagnostic yield. Endolumenal functional lumen imaging probe (EndoFLIP), an emerging technology uses impedance planimetry to provide cross sectional area, distensibility and diameter of a hollow organ. EndoFLIP is increasingly used as an adjunct diagnostic tool to provide diagnostic information and to guide therapy for many GI motility disorders.