Dental stem cells: Progress and perspectives

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Aug 20, 2013 (publication date) through Apr 26, 2024

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World Journal of Stomatology

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2218-6263

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stomatol. Aug 20, 2013; 2(3): 35-39
Published online Aug 20, 2013. doi: 10.5321/wjs.v2.i3.35

Table 1 Types of dental pulp stem cells and their properties

Type of stem cells after birth	Dental stem cell properties	Signaling inputs for reparative dentin formation
Stem cells permanently present in the adult tooth: Dental pulp stem cell Periodontal ligament stem cells Apical papilla stem cells Stem cells present in deciduous tooth: Exfoliated deciduous teeth stem cells Stem cells present during crown formation: Dental follicule stem cells	Self-renewal Ability to enter in mitosis in response to appropriate signals and to differentiate towards odonto/osteogenic cells Long-term survival and maintenance of reparative capacity Distinct subpopulations expressing markers of mesenchymal stem cells of the bone marrow (STRO-1, CD44, CD 106, 3G5, CD146, CD90, Sca-1…)	Tooth injury may promotes stem cell recruitment by: Local secreted factors: bioactive extracellular matrix molecules Ca²⁺ release Mechanical inputs: changes in matrix elasticity Diffusible signals emanating from stromal, inflammatory, circulating… cells

Citation: Dimitrova-Nakov S, Harichane Y, Goldberg M, Kellermann O. Dental stem cells: Progress and perspectives. World J Stomatol 2013; 2(3): 35-39
URL: https://www.wjgnet.com/2218-6263/full/v2/i3/35.htm
DOI: https://dx.doi.org/10.5321/wjs.v2.i3.35