Dental stem cells: Progress and perspectives

doi:10.5321/wjs.v2.i3.35

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World Journal of Stomatology

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2218-6263

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stomatol. Aug 20, 2013; 2(3): 35-39
Published online Aug 20, 2013. doi: 10.5321/wjs.v2.i3.35

Dental stem cells: Progress and perspectives

Sasha Dimitrova-Nakov, Yassine Harichane, Michel Goldberg, Odile Kellermann

Sasha Dimitrova-Nakov, Yassine Harichane, Michel Goldberg, Odile Kellermann, Inserm UMR-S 747, UFR Biomédicales des Saints-Pères, Université Paris Descartes, 75006 Paris, France

Author contributions: All authors substantial contributed to conception, design, acquisition of data, and interpretation of data, drafting the article or revising it critically for important intellectual content, and final approval of the version to be published.

Correspondence to: Michel Goldberg, Professor, Inserm UMR-S 747, UFR Biomédicales des Saints-Pères, Université Paris Descartes, 45 rue des Saints-Pères, 75006 Paris, France. mgoldberg.goldberg004@gmail.com

Telephone: +33-1-42863851 Fax: +33-1-42864068

Received: December 13, 2012
Revised: March 28, 2013
Accepted: April 9, 2013
Published online: August 20, 2013

Core Tip

Core tip: The presence of cell populations displaying stem cell properties within the pulp has opened new paths for considering more conservative therapies. Still, dental stem cells research is still confronted with the lack of precise knowledge related to the location and identity of the cells participating to reparative dentin formation. Clonal cell lines derived from the dental sphere may represent valuable tool to answer some questions that are of fundamental importance to stem cell biology and clinical applications. This review discusses some fundamental concepts of dental stem cell biology within the context of regenerative dentistry.