Published online Feb 20, 2015. doi: 10.5321/wjs.v4.i1.29
Peer-review started: September 30, 2014
First decision: October 21, 2014
Revised: November 14, 2014
Accepted: December 3, 2014
Article in press: January 12, 2015
Published online: February 20, 2015
Central giant cell granuloma (CGCG) is found exclusively in jaws. Its etiopathogenesis is unclear; however it is suggested that it can arise as a reactive response to trauma. This report describes an aggressive variety of CGCG which raises a question; can extraction of tooth modify the behavior of CGCG? A 46 years old male had reported with a rapidly increasing intraoral and extraoral swelling of lower jaw following tooth extraction. Radiographic examination revealed a large multilocular lesion involving the body and ramus of mandible which had been proved to be aggressive CGCG on histopathological examination. The importance of radiographic examination prior to extraction of teeth and importance of inclusion of CGCG in jaw swellings associated with mobility of teeth or failure of healing sockets is emphasized.
Core tip: This report describes an aggressive variety of central giant cell granuloma (CGCG) after extraction which raises a question; can extraction of tooth modify the behavior of CGCG? The importance of radiographic examination prior to extraction of teeth and importance of inclusion of CGCG in jaw swellings associated with mobility of teeth or failure of healing sockets is emphasized. Literature about clarity in clinical behavior, radiographic features and various treatment modalities of this one of the bony lesion of jaws are reviewed.