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World J Otorhinolaryngol. Aug 28, 2014; 4(3): 12-16
Published online Aug 28, 2014. doi: 10.5319/wjo.v4.i3.12
Prenatal diagnosis and management of nasal glioma
Richard Fox, Saleh Okhovat, Issa Beegun
Richard Fox, Saleh Okhovat, Issa Beegun, Department of Otolaryngology, West Middlesex University Hospital, Isleworth, Middlesex TW7 6AF, United Kingdom
Author contributions: Fox R performed the literature search; Fox R and Okhovat S screened the cases; Fox R, Okhovat S and Beegun I reviewed the articles and wrote this paper.
Correspondence to: Dr. Richard Fox, Department of Otolaryngology, West Middlesex University Hospital, Twickenham Rd, Isleworth, Middlesex TW7 6AF, United Kingdom. richardfox@doctors.org.uk
Telephone: +44-20-85602121
Received: January 18, 2014
Revised: June 10, 2014
Accepted: July 12, 2014
Published online: August 28, 2014
Core Tip

Core tip: Advances in foetal imaging have increased our detection rate of craniofacial abnormalities in utero. This enables early surgical input providing differential diagnosis, surgical planning, timing of delivery and counselling for families. Seven cases of prenatally diagnosed nasal glioma have been reported. The authors advocate ultrasound and foetal magnetic resonance imaging (MRI) to delineate the lesion, exclude intracranial involvement and monitor size. Foetal MRI also provides accurate delineation of the upper aerodigestive tract, allowing clinicians to anticipate airway compromise, in this otherwise benign condition. Early surgical resection is advised, for better aesthetic outcomes and to ensure normal ocular development.