Current approach to disseminated intravascular coagulation related to sepsis - organ failure type

Table 3 Treatment recommendations amongst different types of disseminated intravascular coagulation

Dysfunction	Recommended treatment
Pre-DIC	Treat cause and
	UFH 70 IU/kg per day or
	LWMH anti-Xa target: 0.8-1.2
Multiple organ failure	Treat cause and
	AT 30 IU/kg per day of 3 d
Hemorrhagic	Treat cause and
	Hemo-transfusion
	Anti-fibrinolytics
	Protease synthetic inhibitor
Massive hemorrhage	Treat cause and
	Hemo-transfusion
	Anti-fibrinolytics
	Protease synthetic inhibitor

DIC: Disseminated intravascular coagulopathy; UFH: Unfractionated heparin; LWMH: Low molecular weight heparin; Xa: Activated X factor; AT: Anti-thrombin.