Review
Copyright ©2013 Baishideng. All rights reserved.
World J Hematol. May 6, 2013; 2(2): 44-58
Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.44
Another look at the life of a neutrophil
Siroon Bekkering, Ruurd Torensma
Siroon Bekkering, Ruurd Torensma, Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, 6500HB Nijmegen, The Netherlands
Author contributions: Bekkering S and Torensma R designed the research and performed the research; Bekkering S wrote the paper and designed the figures; Torensma R edited the paper.
Correspondence to: Dr. Ruurd Torensma, Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, PO Box 9101, NCMLS 278, 6500HB Nijmegen, The Netherlands. r.torensma@ncmls.ru.nl
Telephone: +31-24-3610544 Fax: +31-24-3540339
Received: February 16, 2013
Revised: April 4, 2013
Accepted: April 13, 2013
Published online: May 6, 2013
Core Tip

Core tip: The lifespan of neutrophils is very dependent on the method used to determine it. Neutrophils are stored in pools and traveling from one location to another dependent on the occurrence of inflammation or not. It appears that isolating neutrophils and labeling them shortens their lifespan considerably. Their longer lifespan enables new functions assigned to them recently.