Copyright ©The Author(s) 2015.
World J Dermatol. May 2, 2015; 4(2): 103-107
Published online May 2, 2015. doi: 10.5314/wjd.v4.i2.103
Table 1 Clinical features and three phase treatment of nicolau syndrome
PhaseClinical featuresTreatment
InitialIntense painAnalgesics
ErythemaSystemic antibiotics1
Radiating painNo ice pack
Faintness, syncope
AcuteLivedoid plaqueSystemic steroid
Violaceous patchAnticoagulant agent
NecroticNecrotic indurated plaqueSurgical debridement
Ulceration with necrosisPlastic surgery