d-limonene prevents ultraviolet irradiation: Induced cyclobutane pyrimidine dimers in Skh1 mouse skin

doi:10.5314/wjd.v3.i3.64

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World Journal of Dermatology

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2218-6190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Dermatol. Aug 2, 2014; 3(3): 64-72
Published online Aug 2, 2014. doi: 10.5314/wjd.v3.i3.64

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Figure 3 Immunostaining of N-myc downstream regulating gene 1. Skin samples were obtained 6 d after UVR exposure. A: In control skin little or no NDRG1 was seen in epidermis but low levels were detected in sebaceous glands, Control; B: 100% d-limonene alone, mouse skin exposed to UVR strongly expressed NDRG1 both in epidermis and sebaceous glands (C-E); C: UVR alone; D: UVR + 1.0% d-limonene; E: UVR + 10% d-limonene; F: UVR + 100% d-limonene. Skin exposed to UVR with prior treatment of d-limonene, show significantly reduced NDRG1protein in epidermis and hair follicles (F). UVR: Ultraviolet irradiation; NDRG1: N-myc downstream regulating gene 1.

Citation: Uddin AN, Wu F, Labuda I, Tchou-Wong KM, Burns FJ. d-limonene prevents ultraviolet irradiation: Induced cyclobutane pyrimidine dimers in Skh1 mouse skin. World J Dermatol 2014; 3(3): 64-72
URL: https://www.wjgnet.com/2218-6190/full/v3/i3/64.htm
DOI: https://dx.doi.org/10.5314/wjd.v3.i3.64