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Copyright ©2014 Baishideng Publishing Group Inc.
World J Orthop. Jul 18, 2014; 5(3): 218-224
Published online Jul 18, 2014. doi: 10.5312/wjo.v5.i3.218
Table 1 Overview of 11 studies reporting about prosthesis retention at the site of periprosthetic hip joint infections with regard to publication year, number of patients treated, type of infection, and level of evidence
Ref.Publication yearNumber of patientsType of infectionLevel of evidence
Aboltins et al[6]2007137 early1IV
6 late
Aboltins et al[7]201319All early1III
Anagnostakos et al[8]201012All late2IV
Choi et al[9]201228All early3III
Crockarell et al[10]19984219 early3IV
19 late
4 acute hematogenous
Kelm et al[11]200928All early2IV
Klouche et al[12]201112All early3IV
Lee et al[13]20131910 late3IV
9 acute hematogenous
Tsukayama et al[2]19964135 early3IV
6 acute hematogenous
Waagsbø et al[3]20094030 early4IV
10 late
Westberg et al[14]201338Early3IV
Table 2 Overview of 11 studies reporting about prosthesis retention at the site of periprosthetic hip joint infections with regard to surgical treatment modalities, -complications, infection eradication rate and length of follow-up
Ref.Surgical treatment procedureSurgical complicationsInfection eradication rate
Aboltins et al[6]Debridement, lavage,1/13 aseptic prosthesis loosening92.30%
Change of PE-liner
[Median = 1 (1-4)]
Aboltins et al[7]Debridement, lavage,N.c.d.89.50%
Change of PE-liner
[Median = 3 (3-6)]
Anagnostakos et al[8]Acetabular cup removal +2/12 draining sinus91.60%
Spacer head onto retained stemAfter spacer head implantation;
Mean implantation period 88 (35-270) d1/12 spacer dislocation;
3/12 prosthesis dislocation
Choi et al[9]19/28 debridement, irrigation,5/28 staged revision,50%
Change of PE-liner6/28 repeated debridement,
9/28 debridement, irrigation,4/28 resection arthroplasty
No change of PE-liner
Crockarell et al[10]Debridement1/42 prosthesis dislocation,21%1
1/42 periprosthetic femoral fracture,
1/42 exitus due to sepsis
Kelm et al[11]Debridement, pulsatile lavage,None92.80%
Change of PE-liner,
Vacuum-assisted closure
Klouche et al[12]Debridement, irrigationn.r.75%
Change of PE-liner and femoral head
Lee et al[13]Acetabular cup removal +n.r.89.50%
Spacer head onto retained stem
Tsukayama et al[2]Debridement, change of PE-liner1/35 acetabular component loosening71% (early)
2/6 acetabular component loosening50% (acute hematogenous)
Waagsbø et al[3]Debridement + prosthesis retentionn.r.67.50%
Westberg et al[14]Debridement, pulsatile lavage,8/38 prosthesis dislocation71%
Change of modular prosthesis components
Table 3 Overview of 11 studies reporting about prosthesis retention at the site of periprosthetic hip joint infections with regard to the systemic antibiotic therapy
Study Systemic antibiotic therapy
Aboltins et al[6]All intravenous glycopeptide or beta-lactam for median 10 (3-29) d
All oral rifampicin+fusidic acid for median 17 (6-33) mo
Aboltins et al[7]All intravenous glycopeptide + beta-lactam for median 15 (12-34) d
All oral rifampicin + fucidic acid or ciprofloxacin for median 356 (230-395) d
Anagnostakos et al[8]All intravenous for 4 wk + oral for 2 wk
Choi et al[9]All intravenous for 6 wk
Crockarell et al[10]41/42 intravenous for 29 (2-72) d
26/42 oral after iv For 70 (5-376) d; 3/42 chronic suppression
Kelm et al[11]Intravenous for 2 wk followed by oral for 2 wk
Klouche et al[12]Intravenous for 6 wk followed by oral for 6 wk
Lee et al[13]Intravenous for 4-6 wk
Tsukayama et al[2]Early: intravenous for 4 wk; acute hematogenous: intravenous for 6 wk
Waagsbø et al[3]Overall duration of antibiotic therapy 0.1 (8.2-14.2) wk, of which intravenous 4.4 (4.2-6.1) wk
Westberg et al[14]Overall duration of antibiotic therapy 7 (3-39) wk