Case Control Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Apr 18, 2017; 8(4): 322-328
Published online Apr 18, 2017. doi: 10.5312/wjo.v8.i4.322
Abnormal ground reaction forces lead to a general decline in gait speed in knee osteoarthritis patients
Anatole Vilhelm Wiik, Adeel Aqil, Mads Brevadt, Gareth Jones, Justin Cobb
Anatole Vilhelm Wiik, MSk Lab, Department of Surgery and Cancer, Charing Cross Hospital, London W68RF, United Kingdom
Anatole Vilhelm Wiik, Adeel Aqil, Mads Brevadt, Gareth Jones, Justin Cobb, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom
Author contributions: Wiik AV and Cobb J designed the study; Wiik AV collected the clinical data; Wiik AV and Brevadt M analysed the data; Wiik AV, Aqil A, Brevadt M, Jones G and Cobb J interpreted and wrote the report.
Institutional review board statement: Ethical approval was sought and gained prior to commencement of the trial through the research ethics committee (10/H0807/101). All investigations were conducted in conformity with ethical principles of research, and informed consent for participation in the study was obtained. This work was performed at, Imperial College London, Charing Cross Campus, United Kingdom.
Informed consent statement: All study participants provided informed written consent prior to study enrolment.
Conflict-of-interest statement: No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.
Data sharing statement: Extended dataset available from the corresponding author.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Anatole Vilhelm Wiik, MSk Lab, Department of Surgery and Cancer, Charing Cross Hospital, Fulham Place Road, London W68RF, United Kingdom. a.wiik@imperial.ac.uk
Telephone: +44-20-33130970 Fax: +44-20-33115218
Received: June 17, 2016
Peer-review started: June 17, 2016
First decision: August 16, 2016
Revised: January 1, 2017
Accepted: January 16, 2017
Article in press: January 18, 2017
Published online: April 18, 2017
Core Tip

Core tip: Top walking speed may unmask significant abnormalities which would not be seen at slower walking speeds. The use of impulse rather than solitary peaks in the analysis of ground reaction forces may be more sensitive in detecting significant abnormalities in gait.