Published online Jun 18, 2015. doi: 10.5312/wjo.v6.i5.434
Peer-review started: February 22, 2015
First decision: April 10, 2015
Revised: April 21, 2015
Accepted: May 8, 2015
Article in press: May 11, 2015
Published online: June 18, 2015
Core tip: Lateral ankle sprain is a common orthopedic injury with a high recurrence rate. However, there is no consensus on whether neuromuscular control and proprioception are compromised in unstable ankles, and whether proprioception training can reduce initial and recurrent ankle injuries. The purpose of this review is to discuss the etiology and intervention of initial and recurrent ankle sprains, focusing on the role of neuromuscular control and proprioception at the ankle joint. This review can provide clinicians the knowledge of constructing better examination protocols and rehabilitation programs for individuals with the unstable ankle.