Published online Nov 18, 2015. doi: 10.5312/wjo.v6.i10.754
Peer-review started: May 22, 2015
First decision: July 10, 2015
Revised: August 22, 2015
Accepted: September 25, 2015
Article in press: September 28, 2015
Published online: November 18, 2015
Core tip: The use of cellular therapies for the treatment of orthopedic diseases is one of the pioneering developments in the history of medical research. Many papers have reported on basic research on cellular sources and methods to localize the cells. Although many review articles have been published, papers discussing clinical trial status were not always available. The authors attempted to review not only the research status of cellular therapy but the status of clinical trials which are on-going in the United States. We hope this editorial can help orthopedic surgeons in keeping up to date in their knowledge of clinical and research stage cellular therapy.