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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jan 18, 2015; 6(1): 106-116
Published online Jan 18, 2015. doi: 10.5312/wjo.v6.i1.106
Published online Jan 18, 2015. doi: 10.5312/wjo.v6.i1.106
Hand bone mass in rheumatoid arthritis: A review of the literature
Gamze Kilic, Salih Ozgocmen, Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Erciyes University, School of Medicine, Gevher Nesibe Hospital, 38039 Kayseri, Turkey
Author contributions: Kilic G and Ozgocmen S contributed to the collection and analysis of the data, and drafted the manuscript.
Open-Access: This article is an open-access article which selected by an in-house editor and fully peer-reviewed by external reviewers. It distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Salih Ozgocmen, MD, Professor, Head, Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Erciyes University, School of Medicine, Gevher Nesibe Hospital, Talas Yolu üzeri, 38039 Kayseri, Turkey. sozgocmen@hotmail.com
Telephone: +90-352-2076666
Received: December 29, 2013
Peer-review started: December 30, 2013
First decision: March 12, 2014
Revised: July 11, 2014
Accepted: July 29, 2014
Article in press: July 29, 2014
Published online: January 18, 2015
Peer-review started: December 30, 2013
First decision: March 12, 2014
Revised: July 11, 2014
Accepted: July 29, 2014
Article in press: July 29, 2014
Published online: January 18, 2015
Core Tip
Core tip: Periarticular osteoporosis or osteopenia affecting the hands is an early characteristic sign of bone damage in rheumatoid arthritis (RA). Dual X-ray absorptiometry (DXA) can be considered a reproducible, sensitive and non-invasive method to assess hand bone mineral density (BMD) in early RA. Quantitative measurement of hand bone loss by DXA may be a useful and practical outcome measure in RA and may have predictive value to determine radiographic progression or functional status in patients with early RA. Building up a reference population to obtain objective and accurate T and Z scores for hand BMD is needed.