Published online Nov 18, 2014. doi: 10.5312/wjo.v5.i5.667
Revised: April 28, 2014
Accepted: May 31, 2014
Published online: November 18, 2014
Core tip: Acute periprosthetic joint infection (PJI) is a major complication after total joint arthroplasty, and occurs either postoperatively or via hematogenous spreading. Debridement, antibiotics and implant retention (DAIR), the primary treatment for acute PJI, should be performed as soon as possible after the development of symptoms, and has success rates around 60%-80%. Whether single or multiple debridement procedures are more successful remains unclear. Systemic treatment, based on culture results, is important for all PJI treatments. Various factors for treatment failure can be identified. For acute PJI, DAIR has good success rates, especially in selected patients.