Brief Article
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World J Orthop. Jan 18, 2014; 5(1): 51-56
Published online Jan 18, 2014. doi: 10.5312/wjo.v5.i1.51
Comparative induction of controlled circulation by magnesium and remifentanil in spine surgery
Mohammad R Ghodraty, Mohammad M Homaee, Kourosh Farazmehr, Ali R Nikzad-Jamnani, Masoud Soleymani-Dodaran, Ali R Pournajafian, Nader D Nader
Mohammad R Ghodraty, Mohammad M Homaee, Kourosh Farazmehr, Ali R Nikzad-Jamnani, Ali R Pournajafian, Department of Anesthesiology, Tehran University of Medical Sciences, Tehran 1336616357, Iran
Masoud Soleymani-Dodaran, Department of Public Health, Tehran University of Medical Sciences, Tehran 1336616357, Iran
Nader D Nader, Department of Anesthesiology, University at Buffalo, Buffalo, NY 14215, United States
Author contributions: Ghodraty MR and Nader ND contributed to the experimental design; Ghodraty MR and Homaee MM participated in conducting the experiments and all authors except Nader ND were involved in patient care and obtaining informed consents; Farazmehr K and Nader ND contributed to data analysis and management and manuscript preparation.
Correspondence to: Nader D Nader, MD, PhD, Department of Anesthesiology, University at Buffalo, VA Western NY Healthcare Sys, Rm. 202C, 3495 Bailey Ave, Buffalo, NY 14215, United States. nnader@buffalo.edu
Telephone: +1-716-8628707 Fax: +1-716-3412715
Received: September 5, 2013
Revised: December 10, 2013
Accepted: December 17, 2013
Published online: January 18, 2014
Core Tip

Core tip: We conducted a relatively small sized prospective randomized clinical trial comparing intravenous infusion of remifentanil with magnesium in controlling blood pressure during posterior spine fusion in order to decrease the intraoperative blood loss. Our experiments showed no difference between the two administered regimens in reducing mean arterial blood pressure and intraoperative blood loss, and satisfaction of the operating surgeons.