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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jan 18, 2024; 15(1): 45-51
Published online Jan 18, 2024. doi: 10.5312/wjo.v15.i1.45
Published online Jan 18, 2024. doi: 10.5312/wjo.v15.i1.45
Association between serum estradiol level and appendicular lean mass index in middle-aged postmenopausal women
Fang Jin, Yan-Fei Wang, Zhong-Xin Zhu, Department of Osteoporosis Care and Control, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou 311200, Zhejiang Province, China
Author contributions: Jin F, Wang YF, and Zhu ZX contributed to data collection, analysis and writing of the manuscript; Zhu ZX contributed to study design and editing of the manuscript.
Institutional review board statement: The Institutional Review Board of the National Center for Health Statistics (NCHS) approved the survey protocols (Protocol #2011-17).
Informed consent statement: The datasets analysed during the current study are available at NHANES website. In accordance with ethical guidelines and research standards, informed consent was not required for this database-based study.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
Data sharing statement: The datasets analysed during the current study are available at NHANES website (https://www.cdc.gov/nchs/nhanes/index.htm).
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhong-Xin Zhu, PhD, Doctor, Department of Osteoporosis Care and Control, Xiaoshan Affiliated Hospital of Wenzhou Medical University, No. 199 Shixin South Road, Xiaoshan District, Hangzhou 311200, Zhejiang Province, China. orthozzx@163.com
Received: August 20, 2023
Peer-review started: August 20, 2023
First decision: November 2, 2023
Revised: November 13, 2023
Accepted: December 13, 2023
Article in press: December 13, 2023
Published online: January 18, 2024
Peer-review started: August 20, 2023
First decision: November 2, 2023
Revised: November 13, 2023
Accepted: December 13, 2023
Article in press: December 13, 2023
Published online: January 18, 2024
Core Tip
Core Tip: This paper evaluated the association between serum E2 level and appendicular lean mass index in middle-aged postmenopausal women from the National Health and Nutrition Examination Survey between 2013 and 2016, and found an inverted U-shaped curve relationship between them, with the point of inflection at a serum E2 level of 85 pg/mL.