Osteolysis in total hip arthroplasty in relation to metal ion release: Comparison between monolithic prostheses and different modularities
Francesco Manfreda, Division of Orthopedics and Trauma Surgery, Santa Maria della Misericordia Hospital, Perugia 06100, Italy
Francesco Manfreda, Egzon Bufi, Paolo Ceccarini, Auro Caraffa, Pierluigi Antinolfi, Department of Orthopedics and Traumatology, University of Perugia, Perugia 06100, Italy
Enrico Francesco Florio, Department of Orthopaedic and Traumatology, Infermi Hospital, AUSL Romagna, Rimini 47921, Italy
Giuseppe Rinonapoli, Department of Orthopaedic, University of Perugia, Perugia 06100, Italy
Author contributions: All the authors contributed equally to this work; Manfreda F and Florio E designed the research and collected the data; Ceccarini P and Rinonapoli G analysed the data; Manfreda F and Bufi E wrote the paper; Antinolfi P and Caraffa A contributed to manuscript revision; all authors approved the final version of the manuscript
Institutional review board statement: The study was reviewed and approved by the Internal Board of local Institution.
Informed consent statement: Informed consent statement was waived.
Conflict-of-interest statement: The Authors declare that there is no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at firstname.lastname@example.org. Participants gave informed consent for data sharing.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Francesco Manfreda, MD, Research Scientist, Surgeon, Department of Orthopedics and Traumatology, University of Perugia, Via G. Dottori, Perugia 06100, Italy. email@example.com
Received: April 30, 2021
Peer-review started: April 30, 2021
First decision: June 16, 2021
Revised: June 30, 2021
Accepted: August 23, 2021
Article in press: August 23, 2021
Published online: October 18, 2021