Retrospective Cohort Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2021; 12(10): 760-767
Published online Oct 18, 2021. doi: 10.5312/wjo.v12.i10.760
Clinical outcome after surgery on schwannomas in the extremities
Andreas Saine Granlund, Michala Skovlund Sørensen, Claus Lindkær Jensen, Birthe Højlund Bech, Michael Mørk Petersen
Andreas Saine Granlund, Musculoskeletal Tumor Section, Department of Orthopedic Surgery, Copenhagen University Hospital, Rigshospitalet, Copenhagen 2100, Denmark
Michala Skovlund Sørensen, Department of Orthopedic Surgery, Copenhagen University Hospital, Copenhagen 2200, Denmark
Claus Lindkær Jensen, Michael Mørk Petersen, Musculoskeletal Tumor Section, Department of Orthopedic Surgery, University of Copenhagen, Copenhagen 2100, Denmark
Birthe Højlund Bech, Department of Radiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark
Author contributions: Granlund AS performed the research and wrote the paper; Sørensen MS made the protocol, statistics and supervised the report; Jensen CL gave surgical inputs and supervised the report; Bech BH performed and examined the radiological scanning; Petersen MM supervised the research and acknowledged the final report.
Institutional review board statement: The study was reviewed and approved by the University of Copenhagen Review Board, No. RH-2016-144.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All authors have nothing to disclose.
Data sharing statement: Statistical code and dataset available from the corresponding author at
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Andreas Saine Granlund, MD, Instructor, Surgeon, Musculoskeletal Tumor Section, Department of Orthopedic Surgery, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.
Received: February 5, 2021
Peer-review started: February 5, 2021
First decision: May 3, 2021
Revised: May 16, 2021
Accepted: September 8, 2021
Article in press: September 8, 2021
Published online: October 18, 2021
Core Tip

Core Tip: Schwannoma is a benign slowly growing tumor which is most common in the central nerve system. Peripheral schwannomas can give symptoms as numbness, local- and radiating pain. Recent studies proves surgical excision can be made with low expectations for complications and a high rate of remission. Never the less, some patients show up with consisting and significant symptoms after surgery. Our study showed that location of tumor on the nerve is of importance when evaluating patients’ clinical symptoms post-operatively.