Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2019; 10(10): 371-377
Published online Oct 18, 2019. doi: 10.5312/wjo.v10.i10.371
Published online Oct 18, 2019. doi: 10.5312/wjo.v10.i10.371
Low-velocity simultaneous bilateral femoral neck fracture following long-term antiepileptic therapy: A case report
Mohammed Sadiq, Vikrant Kulkarni, Syed Azher Hussain, Mohammed Ismail, Mayur Nayak, Department of Orthopaedics, ESIC Medical College, Gulbarga, Karnataka 585106, India
Author contributions: Sadiq M, Kulkarni V and Hussain SA were part of the orthopaedics team that operated on the patient; Ismail M assisted in the radiological investigations; Nayak M and Sadiq M performed the literature review and analysed the results.
Informed consent statement: The patient provided informed consent for publication of this case and any related images.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest related to this report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mohammed Sadiq, MD, DNB, Assistant Professor, Department of Orthopaedics, ESIC Medical College, Sedam Road, Gulbarga, Karnataka 585106, India. mdsadiqaiims@gmail.com
Telephone: +91-99-68835869
Received: March 1, 2019
Peer-review started: March 4, 2019
First decision: June 12, 2019
Revised: July 21, 2019
Accepted: September 15, 2019
Article in press: September 15, 2019
Published online: October 18, 2019
Peer-review started: March 4, 2019
First decision: June 12, 2019
Revised: July 21, 2019
Accepted: September 15, 2019
Article in press: September 15, 2019
Published online: October 18, 2019
Core Tip
Core tip: Drug-induced bilateral femoral neck fractures are extremely rare. The injury has been reported to be associated with long-term intake of bisphosphonates, narcotics, anti-retroviral therapy, and antiepileptic drugs. Only one case of simultaneous bilateral femoral neck fracture associated with long-term antiepileptic drug intake has been reported. Our case report of this type of injury further substantiates the association between long-term antiepileptic drug intake and reduced bone mineral density. Through our experience with this case, we recommend that supplementation of calcium, vitamin D and bisphosphonates along with antiepileptic drugs is essential to maintain bone quality and prevent fractures.