Published online Oct 18, 2019. doi: 10.5312/wjo.v10.i10.371
Peer-review started: March 4, 2019
First decision: June 12, 2019
Revised: July 21, 2019
Accepted: September 15, 2019
Article in press: September 15, 2019
Published online: October 18, 2019
Core tip: Drug-induced bilateral femoral neck fractures are extremely rare. The injury has been reported to be associated with long-term intake of bisphosphonates, narcotics, anti-retroviral therapy, and antiepileptic drugs. Only one case of simultaneous bilateral femoral neck fracture associated with long-term antiepileptic drug intake has been reported. Our case report of this type of injury further substantiates the association between long-term antiepileptic drug intake and reduced bone mineral density. Through our experience with this case, we recommend that supplementation of calcium, vitamin D and bisphosphonates along with antiepileptic drugs is essential to maintain bone quality and prevent fractures.