Formation process of extension knee joint contracture following external immobilization in rats
Chen-Xu Zhou, Feng Wang, Yun Zhou, Quan-Bing Zhang, Department of Rehabilitation Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Qiao-Zhou Fang, The Second Clinical Medicine College, Anhui Medical University, Hefei 230000, Anhui Province, China
Author contributions: Zhou CX conceived the study, participated in its design and coordination, and drafted the manuscript; Wang F participated in the design of the study and performed the statistical analyses; Zhou Y participated in its design and coordination, and helped to draft the manuscript; Fang QZ drew the pictures in the manuscript; Zhang QB performed the statistical analysis in the revised manuscript; All authors read and approved the final manuscript.
Supported by Anhui Key Research and Development Program-Population Health, No. 201904a07020067; Anhui Provincial Health Research Project, No. AHWJ2022b063; Clinical Medicine Discipline Construction Project of Anhui Medical University in 2022 (Clinic and Preliminary Co-Construction Discipline Project), No. 2022 lcxkEFY010; 2022 National Natural Science Foundation Incubation Plan, No. 2022GMFY05; Clinical Medicine Discipline Construction Project of Anhui Medical University in 2022 (High-Level Personnel Training Program), No. 2022 lcxkEFY04 and No. 2022 lcxkEFY05.
Institutional animal care and use committee statement: All animal experiments conformed to the internationally accepted principles for the care and use of laboratory animals (Anhui Medical University; protocol no. LLSC20221126, Experimental Animal Ethics Committee of Anhui Medical University, Anhui, China).
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun Zhou, MD, PhD, Chief Physician, Professor, Department of Rehabilitation Medicine, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Economic and Technological Development Zone, Hefei 230601, Anhui, China. firstname.lastname@example.org
Received: April 27, 2023
Peer-review started: April 27, 2023
First decision: June 14, 2023
Revised: June 30, 2023
Accepted: August 21, 2023
Article in press: August 21, 2023
Published online: September 18, 2023