Retrospective Study
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World J Clin Oncol. May 10, 2014; 5(2): 177-190
Published online May 10, 2014. doi: 10.5306/wjco.v5.i2.177
Twenty-five years of research on the effects of exercise training in breast cancer survivors: A systematic review of the literature
Claudio L Battaglini, Robert C Mills, Brett L Phillips, Jordan T Lee, Christina E Story, Marcelo GB Nascimento, Anthony Carl Hackney
Claudio L Battaglini, Robert C Mills, Brett L Phillips, Jordan T Lee, Department of Exercise and Sport Science, Christina Story, Chapel Hill, NC 27599, United States
Claudio L Battaglini, Lineberger Comprehensive Cancer Center, Chapel Hill, NC 27599, United States
Claudio L Battaglini, Robert C Mills, Brett L Phillips, Jordan T Lee, Christina E Story, Anthony Carl Hackney, Exercise Oncology Research Laboratory, University of North Carolina, Chapel Hill, NC 27599, United States
Anthony Carl Hackney, Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
Marcelo GB Nascimento, Centro Universitario de Brasilia (UniCeub), SEPN 707/907-Campus do UniCEUB-Asa Norte-Brasília-DF-70790-075, Brazil
Author contributions: Battaglini CL, Mills RC, Phillips BL, Lee JT, Story CE, Nascimento MGB and Hackney AC contributed to the manuscript.
Correspondence to: Claudio L Battaglini, PhD, Exercise Oncology Research Laboratory, University of North Carolina, 125 Fetzer Hall, CB 8700, Chapel Hill, NC 27599, United States. claudio@email.unc.edu
Telephone: +1-919-8436045 Fax: +1-919-9620489
Received: January 2, 2014
Revised: January 29, 2014
Accepted: April 17, 2014
Published online: May 10, 2014
Core Tip

Core tip: The purpose of this systematic literature review was to investigate the role of exercise training the past 25 years on major physiological-psychological outcomes studied thus far in this patient population. Exercise training appears to be safe for most breast cancer patients and improvements in physiological, psychological, and functional parameters can be attained with regular participation in moderate intensity exercise.