Importance of symptoms acuity for clinical diagnosis of primary sellar atypical teratoid/rhabdoid tumor

doi:10.5306/wjco.v16.i5.106292

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May 24, 2025 (publication date) through May 19, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. May 24, 2025; 16(5): 106292
Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.106292

Importance of symptoms acuity for clinical diagnosis of primary sellar atypical teratoid/rhabdoid tumor

Run Yu

Run Yu, Department of Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90095, United States

Author contributions: Yu R conceived and wrote the papers.

Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Run Yu, Professor, Department of Medicine, University of California, Los Angeles, David Geffen School of Medicine, 200 Medical Plaza Driveway, Los Angeles, CA 90095, United States. runyu@mednet.ucla.edu

Received: February 21, 2025
Revised: March 26, 2025
Accepted: April 8, 2025
Published online: May 24, 2025
Processing time: 87 Days and 5 Hours

Core Tip

Core Tip: The biological and anatomical characteristics of the sella turcica and its surrounding structures determine the nature, order of manifestation, and acuity of the sellar compression symptoms. The acuity of sellar compression symptoms is critically important to make a correct diagnosis of a non-adenoma sellar mass. In particular, rapidly progressive headache and subsequent similarly rapidly progressive visual symptoms in a female with a large sellar mass are pathognomonic of sellar atypical teratoid/rhabdoid tumor.