Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Jul 24, 2019; 10(7): 256-268
Published online Jul 24, 2019. doi: 10.5306/wjco.v10.i7.256
Reirradiation of recurrent breast cancer with proton beam therapy: A case report and literature review
Yi-Lan Lin
Yi-Lan Lin, Department of Radiation Oncology, Rinecker Proton Therapy Center, Munich 81371, Germany
Author contributions: Lin YL performed all the research and interpretive functions for this case report.
Supported by Rinecker Proton Therapy Center, Munich, Germany.
Informed consent statement: After contacting the patient about the planned publication of her case, she provided written authorization.
Conflict-of-interest statement: The author states there are no potential conflicts of interest relevant to this publication.
CARE Checklist (2016) statement: The author has read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Yi-Lan Lin, Chief Physician, Department of Radiation Oncology, Rinecker Proton Therapy Center, Schaeftlarnstr. 133, Munich 81371, Germany.
Telephone: +49-89-724670 Fax: +49-89-72467352
Received: February 8, 2019
Peer-review started: February 12, 2019
First decision: June 7, 2019
Revised: June 22, 2019
Accepted: July 22, 2019
Article in press: July 22, 2019
Published online: July 24, 2019
Core Tip

Core tip: The treatment of recurrent breast cancer is very complex and not standardized. Patients with locoregional recurrence and gross residual tumor despite systemic therapy and surgery demand further options with potentially curative intention. Presented here is a patient with a late locoregionally recurrent breast cancer, showing significant reduction of gross tumor disease after reirradiation by proton beam therapy. In the 2 years since, the patient has remained free of tumor progression.