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Copyright ©The Author(s) 2020.
World J Gastrointest Pharmacol Ther. Apr 10, 2020; 11(1): 1-7
Published online Apr 10, 2020. doi: 10.4292/wjgpt.v11.i1.1
Table 1 The summary of the application of nanomaterials in pancreatic cancer in this study
NanomaterialsExampleFunction
Nanoparticles (NPs)Silica NPsPhotobiological imaging research[24] MRI contrast agent[25]
Albumin NPsWrap anti-proliferation drug (PvD) to target cancer cell[26]
Delivery NPsSafely deliver Gemcitabine to tumor cells and eliminate toxic effects on normal cells[27]
Quantum dots (QDs)Ag2Se QDsImage pancreatic cancer (PC) in vivo[28]
CTC QDsIdentify CD24+ and CD133+ to detect CTCs[29]
ZnO QDsBetter detection of CA19-9 and PC cell[30]
Carbon nanotubes (CNTs)CA19-9 CNTsConstruct a novel immune sensor and more efficient detection of early PC[31]
Multi-walled CNTsBuilt genetic fingerprints of PC[32]
Gold nanoparticlesPEGAuNPsEffectively deliver drugs to tumor cells
Further suppressing cancer cell proliferation and reducing the toxicity to normal cells[33]
Improvement in the efficacy of photothermal chemotherapy in PC[34]
LiposomeCollagenase liposomeProlonging drug release rate at the target site, and effectively improving the efficacy of the drug[35]
Gemcitabine liposomeLocal hyperthermia with liposomes combined with gemcitabine induce cell death and the formation of apoptotic areas[37]