Disease characteristics and long-term outcomes of cyclic vomiting syndrome in Singaporean children

doi:10.4292/wjgpt.v16.i2.103971

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Jun 5, 2025 (publication date) through Jun 6, 2025

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World Journal of Gastrointestinal Pharmacology and Therapeutics

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2150-5349

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Pharmacol Ther. Jun 5, 2025; 16(2): 103971
Published online Jun 5, 2025. doi: 10.4292/wjgpt.v16.i2.103971

Disease characteristics and long-term outcomes of cyclic vomiting syndrome in Singaporean children

Lynette Goh, Jeremy Meng Dao Ho, Fang Kuan Chiou

Lynette Goh, Fang Kuan Chiou, Department of Gastroenterology, Hepatology and Nutrition, KK Women's and Children's Hospital, Singapore 229899, Singapore

Jeremy Meng Dao Ho, Department of Paediatrics, KK Women's and Children's Hospital, Singapore 229899, Singapore

Author contributions: Goh L, Ho JMD performed research and analyzed data; Goh L, Ho JMD, Chiou FK wrote the paper; All authors read and approved the final manuscript.

Institutional review board statement: Ethics approval was obtained from Singhealth Institutional Review Board (2021/2657).

Informed consent statement: Informed consent and assent was obtained.

Conflict-of-interest statement: There are no conflict of interests to declare.

STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.

Data sharing statement: Data sharing not applicable due to ethical restrictions.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Lynette Goh, Department of Gastroenterology, Hepatology and Nutrition, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore. lynette.goh.s.h@singhealth.com.sg

Received: December 12, 2024
Revised: March 13, 2025
Accepted: March 26, 2025
Published online: June 5, 2025
Processing time: 174 Days and 5 Hours

Core Tip

Core Tip: Cyclic vomiting syndrome (CVS) in children can be debilitating. However, there are prophylactic medications available. The nutritional status of children with CVS before and after starting prophylactic medications is unknown. The incidence of CVS associated hypertension has also not been well described. The improvement in nutritional status after starting prophylactic medications should be a consideration for providers to propose prophylactic medications for poor nutritional status.