Sonographic markers for early diagnosis of fetal malformations

doi:10.4329/wjr.v5.i10.356

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Oct 28, 2013 (publication date) through May 7, 2024

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Radiol. Oct 28, 2013; 5(10): 356-371
Published online Oct 28, 2013. doi: 10.4329/wjr.v5.i10.356

Table 1 Sensitivity of sonographic markers of aneuploidies

Markers of aneuploidy	DR (%)	FPR (%)
NT	83
NT+ PAPP-A + β-hCG + AFP + estriol	94	5
Femoral length	40-50	7
Humeral length	50-54	5-6
Humeral length + NT	75
Pyelectasis	17-25	2-3
Hyperechoic bowel	3.3-27	1
Absence of nasal bone	73	0.5
Nasal bone + NT + PAPP-A + β-hCG + AFP + estriol+ maternal age	97
Aberrant right subclavian artery	37.5	1.4

DR: Detection rate; FPR: False-positive rate; NT: Nuchal translucency; PAPP-A: Pregnancy-associated plasma protein; β-hCG: Chorionic gonadotropin; AFP: Alpha-fetoprotein.

Citation: Renna MD, Pisani P, Conversano F, Perrone E, Casciaro E, Renzo GCD, Paola MD, Perrone A, Casciaro S. Sonographic markers for early diagnosis of fetal malformations. World J Radiol 2013; 5(10): 356-371
URL: https://www.wjgnet.com/1949-8470/full/v5/i10/356.htm
DOI: https://dx.doi.org/10.4329/wjr.v5.i10.356