Published online Jun 28, 2014. doi: 10.4329/wjr.v6.i6.301
Revised: February 28, 2014
Accepted: May 8, 2014
Published online: June 28, 2014
Core tip: Huntington’s disease (HD) is a hereditary and fatal neurodegenerative disorder. Although advances in genetics allow identification of individuals carrying the HD gene, much is still unknown about the mechanisms underlying the development of overt clinical symptoms and the transitional period between premanifestation and manifestation of the disease. Neuroimaging techniques such as magnetic resonance imaging and positron emission tomography may be a suitable biomarker for monitoring disease progression in HD and for assessing the efficacy of future disease modifying therapies. In this article, we provide an overview of the findings from neuroimaging techniques in HD.