Published online Oct 28, 2013. doi: 10.4329/wjr.v5.i10.372
Revised: August 29, 2013
Accepted: September 18, 2013
Published online: October 28, 2013
Core tip: Contrast-enhanced ultrasonography (CEUS) is widely used to characterize focal liver lesions. The lung has dual blood supply (pulmonary arteries and systemic bronchial arteries), and theoretically it should be suitable for CEUS evaluation of arterial vascularity. This study suggests that a delayed time to arterial enhancement or an arbitrary score based on the overall CEUS behaviour ≥ 7.5 have high sensitivity and specificity in suggesting the neoplastic nature of pleural or peripheral pulmonary lesions. CEUS could allow for discriminating between lesions which need invasive diagnostic procedures, and those which can be monitored with clinical and instrumental follow-up.