Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Oct 28, 2020; 12(10): 231-246
Published online Oct 28, 2020. doi: 10.4329/wjr.v12.i10.231
Published online Oct 28, 2020. doi: 10.4329/wjr.v12.i10.231
Cardiac functional magnetic resonance imaging at 7T: Image quality optimization and ultra-high field capabilities
El-Sayed H Ibrahim, V Emre Arpinar, Andrew S Nencka, Kevin M Koch, Department of Radiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States
L Tugan Muftuler, Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI 53226, United States
Jadranka Stojanovska, Department of Radiology, University of Michigan, Ann Arbor, MI 48109, United States
Author contributions: Ibrahim EH helped with study design, experiments, image and data analysis, results interpretation, and manuscript writing; Arpinar VE helped with experiments, image and data analysis, and manuscript revision; Muftuler LT helped with study design, experiments, and manuscript revision; Stojanovska J helped with results interpretation and manuscript revision; Nencka AS helped with results interpretation and manuscript revision; Koch KM helped with results interpretation and manuscript revision; and all authors read and approved the final manuscript.
Supported by The Daniel M. Soref Charitable Trust , Center for Imaging Research, Medical College of Wisconsin, United States.
Institutional review board statement: This study was conducted with approval from Medical College of Wisconsin Institutional Review Board, and informed consent was obtained from scanned human subjects.
Conflict-of-interest statement: The authors have no conflicts-of-interest to report.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: El-Sayed H Ibrahim, PhD, Associate Professor, Department of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, United States. eibrahim@mcw.edu
Received: July 17, 2020
Peer-review started: July 17, 2020
First decision: September 21, 2020
Revised: September 27, 2020
Accepted: October 13, 2020
Article in press: October 13, 2020
Published online: October 28, 2020
Peer-review started: July 17, 2020
First decision: September 21, 2020
Revised: September 27, 2020
Accepted: October 13, 2020
Article in press: October 13, 2020
Published online: October 28, 2020
Core Tip
Core Tip: The capabilities of ultra-high-field magnetic resonance imaging (MRI) have not been fully exploited in cardiac functional imaging. In this study, we provide results from phantom and in vivo scans using a multi-channel transceiver modular coil to optimize 7T cardiac MRI functional imaging without the need for conducting B1 shimming or subject-specific system tuning. The results showed that improved regional and global cardiac functional imaging can be achieved at 7T MRI through simple scan set-up adjustment and imaging parameter optimization, which would allow for more streamlined and efficient ultra-high-field cardiac MRI with access to more information and details compared to lower-field imaging.