Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Oct 28, 2018; 10(10): 116-123
Published online Oct 28, 2018. doi: 10.4329/wjr.v10.i10.116
Could intravoxel incoherent motion diffusion-weighted magnetic resonance imaging be feasible and beneficial to the evaluation of gastrointestinal tumors histopathology and the therapeutic response?
Hou-Dong Zuo, Xiao-Ming Zhang
Hou-Dong Zuo, Xiao-Ming Zhang, Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Author contributions: All authors contributed to writing the paper and had full control over preparation of manuscript; all authors approved the final draft manuscript.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Xiao-Ming Zhang, MD, PhD, Professor, Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 63# Wenhua Road, Shunqing District, Nanchong 637000, Sichuan Province, China. cjr.zhxm@vip.163.com
Telephone: +86-817-2262218 Fax: +86-817-2222856
Received: June 23, 2018
Peer-review started: June 24, 2018
First decision: July 19, 2018
Revised: August 2, 2018
Accepted: August 2, 2018
Article in press: August 26, 2018
Published online: October 28, 2018
Core Tip

Core tip: In general, the gastrointestinal tumors (GTs) can be diagnosed by routine computed tomography/magnetic resonance imaging (MRI) and biopsy, but the intravoxel incoherent motion (IVIM), a new emerging MRI technique, plays a important role in the tumor evaluation before and after surgery, and provides more useful information in tumor properties, stage and chemoradiotherapy (CRT) response. What’s more, the quantitative parameters derived from IVIM, including D, D* and f, can gain an insight into tumor tissue physiology changes and simultaneously reflect the microenvironment, microcirculation in the capillary network and diffusion in tumor tissues, thus, new imaging biomarkers for monitoring and evaluating the tumor and the CRT response in GTs.