Opinion Review
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Aug 28, 2022; 14(8): 249-255
Published online Aug 28, 2022. doi: 10.4329/wjr.v14.i8.249
Augmenting prostate magnetic resonance imaging reporting to incorporate diagnostic recommendations based upon clinical risk calculators
Karisma Gupta, Jordan D Perchik, Andrew M Fang, Kristin K Porter, Soroush Rais-Bahrami
Karisma Gupta, Department of Radiology, University of Washington, Seattle, WA 98195, United States
Jordan D Perchik, Kristin K Porter, Soroush Rais-Bahrami, Department of Radiology, University of Alabama at Birmingham, Birmingham, AL 35233, United States
Andrew M Fang, Soroush Rais-Bahrami, Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35233, United States
Soroush Rais-Bahrami, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35233, United States
Author contributions: Porter KK and Rais-Bahrami S contributed equally to this work; Porter KK and Rais-Bahrami S designed the study; Gupta K, Perchik JD, Fang AM, Porter KK, and Rais-Bahrami S contributed to authoring the manuscript and critically reviewing and revising the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: Rais-Bahrami S serves as a consultant to Philips/InVivo Corp, Genomic Health Inc, Blue Earth Diagnostics, Bayer Healthcare, UroViu Corp, and Intuitive Surgical.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Soroush Rais-Bahrami, MD, Associate Professor, Departments of Urology and Radiology, University of Alabama at Birmingham, Faculty Office Tower 1107 510 20th Street South, Birmingham, AL 35233, United States. soroushraisbahrami@gmail.com
Received: March 22, 2022
Peer-review started: March 22, 2022
First decision: June 16, 2022
Revised: June 27, 2022
Accepted: July 25, 2022
Article in press: July 25, 2022
Published online: August 28, 2022
Abstract

Risk calculators have offered a viable tool for clinicians to stratify patients at risk of prostate cancer (PCa) and to mitigate the low sensitivity and specificity of screening prostate specific antigen (PSA). While initially based on clinical and demographic data, incorporation of multiparametric magnetic resonance imaging (MRI) and the validated prostate imaging reporting and data system suspicion scoring system has standardized and improved risk stratification beyond the use of PSA and patient parameters alone. Biopsy-naïve patients with lower risk profiles for harboring clinically significant PCa are often subjected to uncomfortable, invasive, and potentially unnecessary prostate biopsy procedures. Incorporating risk calculator data into prostate MRI reports can broaden the role of radiologists, improve communication with clinicians primarily managing these patients, and help guide clinical care in directing the screening, detection, and risk stratification of PCa.

Keywords: Prostatic adenocarcinoma, Multiparametric magnetic resonance imaging, Nomograms, Risk calculators, Biopsy

Core Tip: Incorporating risk calculator data into prostate magnetic resonance imaging reports can broaden the role of radiologists, improve communication with clinicians primarily managing these patients, and help guide clinical care in directing the screening, detection, and risk stratification of prostate cancer.