National adult mortality trends due to chronic kidney disease-related atrial fibrillation in the United States from year 2011-2020

Table 1 Chronic kidney disease related atrial fibrillation stratified by sex and race in United States, 2011 to 2020

Year	Overall	Women	Men	NH White	NH Black or African American	NH Asian or Pacific Islander	NH American Indian or Alaska Native	Hispanic or Latino	Population
2011	10682	5237	5445	8897	1001	286	40	439	164802438
2012	12411	6048	6363	10273	1145	301	52	611	166516716
2013	7227	3407	3820	6136	637	130	34	282	168240727
2014	7694	3674	4020	6488	676	172	38	305	170292776
2015	9022	4247	4775	7682	721	189	34	367	172416615
2016	9990	4698	5292	8379	876	242	49	423	173964174
2017	11329	5309	6020	9447	1041	275	35	511	176104659
2018	12366	5764	6602	10314	1114	282	52	581	177613416
2019	13650	6475	7175	11364	1181	339	66	675	179040846
2020	16362	7466	8896	13532	1534	385	81	816	180565367
Total	110733	52325	58408	92512	9926	2601	481	5010	1729557734

NH: Non-Hispanic.

Table 2 Chronic kidney disease related atrial fibrillation, stratified by place of death in United States, 2011 to 2020

Year	Medical facility	Nursing home/long-term care facility	Hospices	Home
2011	4691	2843	469	2241
2012	5181	3301	698	2731
2013	3222	1813	401	1472
2014	3464	1922	405	1633
2015	3832	2300	627	1953
2016	4347	2417	697	2197
2017	4797	2721	845	2549
2018	5184	2983	911	2896
2019	5542	3144	1121	3332
2020	6811	3340	1094	4495
Total	47071	26784	7268	25499

Table 3 Annual percent change of chronic kidney disease related atrial fibrillation age-adjusted mortality rates per 100000, in the United States, 2011 to 2020

Year interval	APC (95%CI)
Overall
2011 to 2014	-15.49 (-30.23 to -5.55)
2014 to 2020	10.12 (6.49-17.41)
Men
2011 to 2014	-14.89 (-30.44 to -4.06)
2014 to 2020	9.91 (6.10-19.62)
Women
2011 to 2014	-15.91 (-31.40 to -5.17)
2014 to 2020	10.09 (6.16-18.51)
NH White
2011 to 2014	-14.49 (-29.44 to -4.17)
2014 to 2020	10.63 (7.09-18.11)
NH Black or African American
2011 to 2014	-19.23 (-36.71 to -6.14)
2014 to 2020	10.28 (4.94-26.47)
NH American Indian or Alaska native
2011 to 2017	-7.17 (-21.47 to -1.42)
2017 to 2020	23.97 (8.45-51.18)
Hispanic or Latino
2011 to 2014	-22.94 (-41.00 to -7.62)
2014 to 2020	11.59 (6.08-22.08)
NH Asian or Pacific Islander
2011 to 2013	-34.76 (-47.48 to -11.50)
2013 to 2020	6.48 (2.15-19.29)
Nonmetropolitan areas
2011 to 2013	-20.90 (-29.08 to -8.27)
2013 to 2020	10.17 (7.65-14.83)
Metropolitan area
2011 to 2014	-15.59 (-30.45 to -5.43)
2014 to 2020	9.80 (6.08-17.61)
Northeast region
2011 to 2014	-13.42 (-26.72 to -4.41)
2014 to 2020	9.12 (5.94-15.48)
Midwest region
2011 to 2014	-15.05 (-30.78 to -4.00)
2014 to 2020	11.41 (7.69-19.80)
South region
2011 to 2014	-14.92 (-30.38 to -4.04)
2014 to 2020	10.67 (6.94-19.25)
West region
2011 to 2014	-16.99 (-32.90 to -6.03)
2014 to 2020	8.71 (4.51-18.15)

Indicates that the annual percentage change is significantly different from zero at α = 0.05. CI: Confidence interval; APC: Annual percent change; NH: Non-Hispanic.

Table 4 Overall and sex-stratified chronic kidney disease related atrial fibrillation age-adjusted mortality rates per 10000, in the United States, 2011 to 2020 (age-adjusted rate, 95% confidence interval)

Year	Men	Women	Overall
2011	8.1 (7.9-8.3)	4.9 (4.8-5.1)	6.2 (6.1-6.3)
2012	9.2 (9-9.4)	5.5 (5.4-5.7)	7 (6.9-7.1)
2013	5.4 (5.2-5.6)	3 (2.9-3.1)	4 (3.9-4.1)
2014	5.5 (5.3-5.7)	3.2 (3.1-3.3)	4.1 (4-4.2)
2015	6.3 (6.1-6.5)	3.6 (3.5-3.8)	4.7 (4.6-4.8)
2016	6.8 (6.6-7)	4 (3.8-4.1)	5.1 (5-5.2)
2017	7.5 (7.4-7.7)	4.4 (4.3-4.5)	5.7 (5.6-5.8)
2018	8 (7.8-8.2)	4.7 (4.6-4.8)	6 (5.9-6.1)
2019	8.5 (8.3-8.7)	5.2 (5.1-5.3)	6.6 (6.4-6.7)
2020	10.3 (10.1-10.5)	5.9 (5.7-6)	7.7 (7.6-7.8)
Total	7.6 (7.6-7.7)	4.5 (4.4-4.5)	5.8 (5.7-5.8)

Table 5 Chronic kidney disease related atrial fibrillation age-adjusted mortality rates per 10000, stratified by races in the United States, 2011 to 2020 (age-adjusted rate, 95% confidence interval)

Year	NH White	NH Black or African American	NH American Indian or Alaska native	Hispanic or Latino	NH Asian or Pacific Islander
2011	6.3 (6.1-6.4)	6.9 (6.5-7.4)	5 (3.5-6.9)	3.8 (3.4-4.1)	4.8 (4.2-5.4)
2012	7.1 (6.9-7.2)	7.6 (7.1-8)	6.3 (4.6-8.4)	5 (4.6-5.4)	4.7 (4.2-5.2)
2013	4.1 (4-4.2)	4.2 (3.8-4.5)	4.1 (2.8-5.8)	2.2 (1.9-2.4)	1.9 (1.6-2.2)
2014	4.3 (4.2-4.4)	4.1 (3.8-4.4)	4.4 (3.1-6)	2.2 (2-2.5)	2.3 (2-2.7)
2015	5 (4.9-5.1)	4.3 (3.9-4.6)	3.2 (2.2-4.5)	2.5 (2.2-2.7)	2.4 (2-2.7)
2016	5.4 (5.3-5.5)	5 (4.7-5.4)	4.4 (3.2-5.9)	2.8 (2.5-3)	2.9 (2.5-3.3)
2017	6 (5.9-6.1)	5.7 (5.3-6.1)	3.4 (2.3-4.7)	3.1 (2.8-3.4)	3.1 (2.7-3.4)
2018	6.4 (6.3-6.6)	6 (5.6-6.3)	4.4 (3.3-5.9)	3.3 (3-3.6)	3 (2.6-3.3)
2019	7 (6.9-7.1)	6.1 (5.8-6.5)	5.6 (4.3-7.2)	3.8 (3.5-4.1)	3.4 (3-3.8)
2020	8.3 (8.1-8.4)	7.8 (7.4-8.2)	6.6 (5.2-8.2)	4.3 (4-4.6)	3.7 (3.3-4)
Total	7.8 (0-6)	5.1 (0.1-5.8)	4.2 (0.2-4.8)	2.2 (0-3.3)	2.7 (0.1-3.2)

NH: Non-Hispanic.

Table 6 Chronic kidney disease related atrial fibrillation age-adjusted mortality rates per 10000, stratified by states, in United States, 2011 to 2020

State	Age-adjusted rate (95%CI)
Alabama	3.8 (3.6-4.1)
Alaska	5.3 (4.4-6.3)
Arizona	3.9 (3.7-4)
Arkansas	4.1 (3.8-4.4)
California	6.3 (6.2-6.5)
Colorado	7.6 (7.3-8)
Connecticut	4.7 (4.4-5)
Delaware	5.4 (4.8-6)
District of Columbia	4.5 (3.8-5.3)
Florida	3.3 (3.2-3.4)
Georgia	3.6 (3.4-3.7)
Hawaii	4.3 (3.9-4.7)
Idaho	5.8 (5.3-6.3)
Illinois	4.2 (4.1-4.4)
Indiana	8.9 (8.6-9.2)
Iowa	6.5 (6.2-6.9)
Kansas	4.2 (3.9-4.5)
Kentucky	7.7 (7.4-8.1)
Louisiana	3.4 (3.2-3.7)
Maine	5.9 (5.4-6.4)
Maryland	6.4 (6.1-6.7)
Massachusetts	5.2 (5-5.4)
Michigan	5.1 (4.9-5.3)
Minnesota	10.9 (10.6-11.3)
Mississippi	3.8 (3.5-4.1)
Missouri	4.7 (4.5-4.9)
Montana	5.6 (5.1-6.2)
Nebraska	8.7 (8.1-9.2)
Nevada	2.6 (2.3-2.9)
New Hampshire	7.3 (6.8-7.9)
New Jersey	5.2 (5-5.4)
New Mexico	3.3 (3-3.6)
New York	3.5 (3.4-3.6)
North Carolina	6.2 (6-6.4)
North Dakota	8.9 (8.1-9.8)
Ohio	6.5 (6.3-6.7)
Oklahoma	7.5 (7.1-7.8)
Oregon	9.8 (9.4-10.2)
Pennsylvania	6.9 (6.7-7)
Rhode Island	7.3 (6.7-7.9)
South Carolina	7 (6.7-7.3)
South Dakota	6.6 (6-7.3)
Tennessee	6.9 (6.7-7.2)
Texas	6.5 (6.3-6.6)
Utah	5.3 (4.9-5.7)
Vermont	8.1 (7.3-9)
Virginia	5.3 (5.1-5.5)
Washington	9 (8.7-9.3)
West Virginia	7.7 (7.2-8.2)
Wisconsin	8.4 (8.1-8.6)
Wyoming	6.2 (5.3-7)

CI: Confidence interval.

Table 7 Chronic kidney disease related atrial fibrillation age-adjusted mortality rates per 10000, stratified by census region in United States, 2011 to 2020 (age-adjusted rate, 95% confidence interval)

Year	Northeast	Midwest	South	West
2011	5.5 (5.2-5.7)	6.7 (6.4-6.9)	5.5 (5.3-5.7)	7.3 (7-7.6)
2012	6.1 (5.9-6.4)	7.6 (7.3-7.8)	6.2 (6-6.4)	8.2 (7.9-8.5)
2013	3.7 (3.5-3.9)	4.4 (4.2-4.6)	3.6 (3.4-3.7)	4.3 (4.1-4.5)
2014	3.9 (3.7-4.1)	4.5 (4.3-4.7)	3.7 (3.6-3.9)	4.6 (4.4-4.8)
2015	4.3 (4.1-4.5)	5.3 (5.1-5.6)	4.3 (4.1-4.4)	5.1 (4.9-5.3)
2016	4.7 (4.5-5)	5.7 (5.5-5.9)	4.7 (4.5-4.8)	5.6 (5.4-5.8)
2017	5.2 (4.9-5.4)	6.4 (6.2-6.7)	5.1 (5-5.3)	6.2 (5.9-6.4)
2018	5.5 (5.2-5.7)	7 (6.7-7.2)	5.6 (5.4-5.8)	6.3 (6-6.5)
2019	5.8 (5.5-6)	7.6 (7.4-7.9)	6 (5.8-6.1)	7.1 (6.9-7.4)
2020	6.8 (6.6-7.1)	9.1 (8.9-9.4)	7.2 (7-7.4)	7.9 (7.6-8.1)
Total	5.2 (5.1-5.2)	6.5 (6.4-6.6)	5.2 (5.2-5.3)	6.3 (6.2-6.4)

Table 8 Chronic kidney disease related atrial fibrillation age-adjusted mortality rates per 10000, stratified by urban-rural classification, in United states, 2011 to 2020 (age-adjusted rate, 95% confidence interval)

Year	Metropolitan	Nonmetropolitan
2011	6.1 (6-6.2)	6.6 (6.3-6.9)
2012	6.9 (6.8-7.1)	7.3 (7-7.6)
2013	3.9 (3.8-4)	4.2 (3.9-4.4)
2014	4 (3.9-4.1)	4.5 (4.2-4.7)
2015	4.6 (4.5-4.7)	5.3 (5-5.5)
2016	5 (4.9-5.1)	5.7 (5.4-6)
2017	5.5 (5.4-5.6)	6.4 (6.2-6.7)
2018	5.9 (5.8-6)	6.7 (6.4-7)
2019	6.4 (6.2-6.5)	7.7 (7.4-7.9)
2020	7.4 (7.3-7.5)	9.2 (8.9-9.5)
Total	5.6 (5.6-5.7)	6.4 (6.3-6.5)