Meta-Analysis
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Aug 26, 2025; 17(8): 109738
Published online Aug 26, 2025. doi: 10.4330/wjc.v17.i8.109738
Sex-based outcomes following thoracic endovascular aortic repair for acute complicated type B aortic dissection: A meta-analysis
Muneeb Khawar, Syed Abdullah Shah, Aqsa Komel, Zainab Anfaal, Umad Ali, Moosa Mubarik, Muhammad Khan Buhadur Ali, Awon Muhammad, Muneeb Saifullah, Mirza Muhammad Hadeed Khawar, Abdul Qadeer, Saad Ur Rahman, Mobeen Haider, Abbas Muhammad Mehdi
Muneeb Khawar, Syed Abdullah Shah, Umad Ali, Awon Muhammad, Muneeb Saifullah, Department of Medicine, King Edward Medical University, Lahore 54000, Punjab, Pakistan
Aqsa Komel, Moosa Mubarik, Department of Medicine, Nishtar Medical University, Multan 66000, Punjab, Pakistan
Zainab Anfaal, Department of Medicine, Khyber Medical College, Peshawar 25120, Khyber Pakhtunkhwa, Pakistan
Muhammad Khan Buhadur Ali, Department of Medicine and Surgery, King Edward Medical University, Lahore 54000, Punjab, Pakistan
Mirza Muhammad Hadeed Khawar, Department of Medicine, Services Institute of Medical Sciences, Lahore 54000, Punjab, Pakistan
Abdul Qadeer, Department of Medicine, Mayo Clinic Phoenix, Arizona, AZ 5777 E, United States
Saad Ur Rahman, Department of Medicine, Lahey Hospital and Medical Center, Burlington, MA 01805, United States
Mobeen Haider, Department of Medicine, West Virginia University, Morgantown, WV 26506, United States
Abbas Muhammad Mehdi, Department of Medicine, International School of Medicine, International University of Kyrgyzstan, Bishkek 720065, Kyrgyzstan
Author contributions: Khawar M, Shah SA, Komel A lead conceptualization, methodology and formal analysis and wrote and reviewed the manuscript; Anfaal Z, Ali U, Mubarik M, Ali MKB, Muhammad A lead software, validation, investigation and wrote and reviewed the manuscript; Saifullah M, Khawar MMH, Qadeer A, Rehman SU, Haider M and Mehdi AM wrote and reviewed the manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abbas Muhammad Mehdi, MD, Department of Medicine, International School of Medicine, International University of Kyrgyzstan, 6 Seven April Street, Bishkek 720065, Kyrgyzstan. malikmehdi0508@gmail.com
Received: May 21, 2025
Revised: June 13, 2025
Accepted: August 4, 2025
Published online: August 26, 2025
Processing time: 92 Days and 10.1 Hours
Core Tip

Core Tip: This meta-analysis demonstrates that while most clinical outcomes following thoracic endovascular aortic repair (TEVAR) for acute complicated type B aortic dissection are comparable between sexes, male patients face a higher risk of postoperative acute kidney injury (AKI). By addressing modifiable risk factors and exploring innovative care models, clinicians can reduce the burden of AKI and enhance care for patients undergoing TEVAR.