Evidence Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Aug 26, 2021; 13(8): 254-270
Published online Aug 26, 2021. doi: 10.4330/wjc.v13.i8.254
Multimodality imaging in the diagnosis and management of prosthetic valve endocarditis: A contemporary narrative review
Saberio Lo Presti, Tarec K Elajami, Mohammad Zmaili, Reza Reyaldeen, Bo Xu
Saberio Lo Presti, Reza Reyaldeen, Advanced Cardiac Imaging Fellows, Sydell and Arnold Miller Family Heart Vascular and Thoracic Institute at Cleveland Clinic, Cleveland, OH 44195, United States
Tarec K Elajami, Department of Cardiology, Mount Sinai Medical Center, Miami Beach, FL 33140, United States
Mohammad Zmaili, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Bo Xu, Section of Cardiovascular Imaging in the Robert and Suzanne Tomsich, Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart Vascular and Thoracic Institute at Cleveland Clinic, Cleveland, OH 44195, United States
Author contributions: All authors contributed to the literature review, drafting of the manuscript and approval of the final version.
Conflict-of-interest statement: All authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bo Xu, MD, FRACP, FACC, FASE, Multimodality Imaging Cardiologist, Section of Cardiovascular Imaging in the Robert and Suzanne Tomsich, Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart Vascular and Thoracic Institute at Cleveland Clinic, Cleveland, OH 44195, United States. xub@ccf.org
Received: March 11, 2021
Peer-review started: March 11, 2021
First decision: April 6, 2021
Revised: June 24, 2021
Accepted: July 26, 2021
Article in press: July 26, 2021
Published online: August 26, 2021
Core Tip

Core Tip: Prosthetic valve endocarditis comprises up to 30% of all cases of infective endocarditis with a reported in-hospital mortality of 14%-22% and 1-year mortality as high as 40%. Its prompt diagnosis, although often challenging, is of critical importance to prevent deleterious consequences for patients. Advances in the field of 3-dimensional-echocardiography and the increased applications of adjuvant, complementary imaging modalities, including 18-fluorodeoxyglucose positron emission tomography/ computed tomography, have enhanced the diagnostic accuracy. In the present narrative review, we discuss the epidemiology, clinical manifestations, management principles, and advantages and limitations of various imaging modalities available for the diagnosis and management of prosthetic valve endocarditis.