Published online Jul 26, 2022. doi: 10.4330/wjc.v14.i7.427
Peer-review started: April 7, 2022
First decision: May 12, 2022
Revised: May 13, 2022
Accepted: June 17, 2022
Article in press: June 17, 2022
Published online: July 26, 2022
Recent studies have reported a strong association between human immunodeficiency virus (HIV) infection and cardiovascular diseases. However, studies examining the trend of cardiovascular diseases in people living with HIV on a national level have been lacking.
The trends of cardiovascular diseases in people living with HIV have not been sufficiently examined using nationally representative database.
To demonstrate that the burden of cardiovascular disease in people living with HIV has been increasing in the recent decade, emphasizing the need for continual efforts to address the excess cardiovascular risks in this vulnerable population.
We retrospectively examined the National Inpatient Sample from 2008 to 2018 to analyze the trends in the hospitalizations for various cardiovascular diseases in people living with HIV. In addition, we looked at the trends of in-hospital mortality, length of hospital stay, and total hospital charge. Cochran-Armitage test and simple linear regression were used to examine the trends of categorical and continuous variables, respectively.
Hospitalizations for heart failure, ischemic heart disease, and cerebrovascular disease in people living with HIV showed an increasing trend, while the total number of hospitalizations in people with living HIV showed a decreasing trend from 2008 to 2018. The trend of in-hospital mortality and length of stay were variable in contrast to total hospital charge, which demonstrated a substantially increasing trend over the decade.
Nationally representative data showed that the burden of cardiovascular diseases in people living with HIV has been significantly.
Further studies and preventative measures are needed to mitigate the additional cardiovascular burden in people living with HIV.