Estévez-Loureiro R, López-Sainz &, Pérez de Prado A, Cuellas C, Calviño Santos R, Alonso-Orcajo N, Salgado Fernández J, Vázquez-Rodríguez JM, López-Benito M, Fernández-Vázquez F. Timely reperfusion for ST-segment elevation myocardial infarction: Effect of direct transfer to primary angioplasty on time delays and clinical outcomes. World J Cardiol 2014; 6(6): 424-433 [PMID: 24976914 DOI: 10.4330/wjc.v6.i6.424]
Corresponding Author of This Article
Rodrigo Estévez-Loureiro, MD, PhD, Division of Cardiology, Complejo Asistencial Universitario de León (CAULE), Altos de Nava s/n, 24071 Leon, Spain. roiestevez@hotmail.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Jun 26, 2014; 6(6): 424-433 Published online Jun 26, 2014. doi: 10.4330/wjc.v6.i6.424
Timely reperfusion for ST-segment elevation myocardial infarction: Effect of direct transfer to primary angioplasty on time delays and clinical outcomes
Rodrigo Estévez-Loureiro, Ángela López-Sainz, Armando Pérez de Prado, Carlos Cuellas, Ramón Calviño Santos, Norberto Alonso-Orcajo, Jorge Salgado Fernández, Jose Manuel Vázquez-Rodríguez, Maria López-Benito, Felipe Fernández-Vázquez
Rodrigo Estévez-Loureiro, Armando Pérez de Prado, Carlos Cuellas, Norberto Alonso-Orcajo, Maria López-Benito, Felipe Fernández-Vázquez, Division of Cardiology, Complejo Asistencial Universitario de León (CAULE), 24071 Leon, Spain
Ángela López-Sainz, Ramón Calviño Santos, Jorge Salgado Fernández, Jose Manuel Vázquez-Rodríguez, Division of Cardiology, Complejo Hospitalario Universitario A Coruña (CHUAC), 15006 La Coruña, Spain
Author contributions: López-Sainz A, Pérez de Prado A, Cuellas C and López-Benito M performed research; Calviño-Santos R, Salgado Fernández J and Vázquez-Rodríguez JM reviewed critically the literature; Estévez-Loureiro R wrote the paper; Alonso Orcajo N and Fernández-Vázquez F reviewed the text and gave final approval.
Correspondence to: Rodrigo Estévez-Loureiro, MD, PhD, Division of Cardiology, Complejo Asistencial Universitario de León (CAULE), Altos de Nava s/n, 24071 Leon, Spain. roiestevez@hotmail.com
Telephone: +34-987-237400 Fax: +34-987-233322
Received: December 27, 2013 Revised: January 27, 2014 Accepted: April 9, 2014 Published online: June 26, 2014
Abstract
Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy for patients presenting with ST-segment elevation myocardial infarction (STEMI) when it can be performed expeditiously and by experienced operators. In spite of excellent clinical results this technique is associated with longer delays than thrombolysis and this fact may nullify the benefit of selecting this therapeutic option. Several strategies have been proposed to decrease the temporal delays to deliver PPCI. Among them, prehospital diagnosis and direct transfer to the cath lab, by-passing the emergency department of hospitals, has emerged as an attractive way of diminishing delays. The purpose of this review is to address the effect of direct transfer on time delays and clinical events of patients with STEMI treated by PPCI.
Core tip: Primary angioplasty has emerged as the preferred reperfusion modality for patients with ST-segment elevation myocardial infarction. However, this treatment is associated with longer delays. Several strategies have been proposed to overcome these drawbacks. This review aimed to highlight the effect of a direct transfer strategy on time delays reduction and in the prognosis of this subgroup of patients.
