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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Biol Chem. Sep 27, 2020; 11(2): 62-75
Published online Sep 27, 2020. doi: 10.4331/wjbc.v11.i2.62
Published online Sep 27, 2020. doi: 10.4331/wjbc.v11.i2.62
Epigenetic basis of Alzheimer disease
Angeles C Tecalco-Cruz, Programa en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Mexico 03100, Mexico
Josué O Ramírez-Jarquín, División de neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico 04510, Mexico
María E Alvarez-Sánchez, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad, Mexico 03100, Mexico
Jesus Zepeda-Cervantes, Biología celular y de desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico 04510, Mexico
Author contributions: Tecalco-Cruz AC participated in the research, organization of this article and wrote the manuscript; Ramírez-Jarquín JO, participated in the all figures of this article; Ramírez-Jarquín JO, Alvarez–Sánchez ME and Zepeda-Cervantes J participated in the research, and improvement of this article.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Angeles C Tecalco-Cruz, PhD, Academic Research, Programa en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Av. San Lorenzo No. 290. Apdo, Mexico 03100, Mexico. angeles.tecalco@uacm.edu.mx
Received: May 13, 2020
Peer-review started: May 13, 2020
First decision: June 15, 2020
Revised: June 30, 2020
Accepted: September 10, 2020
Article in press: September 10, 2020
Published online: September 27, 2020
Peer-review started: May 13, 2020
First decision: June 15, 2020
Revised: June 30, 2020
Accepted: September 10, 2020
Article in press: September 10, 2020
Published online: September 27, 2020
Core Tip
Core Tip: The deregulation of non-coding ribonucleic acids and epigenetic modifications have been described in Alzheimer disease (AD). These changes have been observed in different brain regions related to learning and memory, processes that are affected in AD. The epigenetic basics in the progression of AD were integrated into this review.