Role of neutrophil-to-lymphocyte, platelet-to-lymphocyte, and monocyte-to-lymphocyte ratios in rectal cancer prognosis

Table 1 Inflammatory index values before and after surgery

Group	Case	NLR	PLR	MLR
Preoperative	180	4.58 ± 1.01	182.84 ± 52.19	0.34 ± 0.18
Postoperative	180	2.86 ± 0.82	108.49 ± 41.03	0.21 ± 0.14
t		17.738	15.026	7.649
P value		< 0.001	< 0.001	< 0.001

Data are presented as mean ± SD. MLR: Monocyte-to-lymphocyte ratio; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio.

Table 2 Expression of postoperative inflammatory indicators in patients with different prognoses

Group	Case	NLR	PLR	MLR
Good prognosis	152	2.48 ± 0.48	92.48 ± 38.18	0.17 ± 0.10
Poor prognosis	28	3.84 ± 0.51	121.07 ± 41.96	0.25 ± 0.16
t		13.644	3.585	3.498
P value		< 0.001	< 0.001	0.001

Data are presented as mean ± SD. MLR: Monocyte-to-lymphocyte ratio; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio.

Table 3 Predictive analysis of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio

Index	AUC	Sensitivity, %	Specificity, %	Youden index	SE	95%CI
NLR	0.660	67.86	54.61	0.310	0.0563	0.586-0.729
PLR	0.668	75.00	55.30	0.303	0.0553	0.595-0.737
MLR	0.635	60.71	48.03	0.314	0.0657	0.560-0.706
Joint indicators	0.825a	89.29	90.79	0.602	0.0496	0.761-0.877

^aP < 0.05 indicates statistical significance compared with the other indicators. MLR: Monocyte-to-lymphocyte ratio; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; AUC: Area under the curve; CI: Confidence interval; SE: Standard error.