Predicting risk of post-hepatectomy liver failure in patients undergoing liver resection with controlled low central venous pressure

Figure 1 Flow chart of this study. CLCVP: Controlled low central venous pressure; PHLF: Post-hepatectomy liver failure; LASSO: Least absolute shrinkage and selection operator.

Figure 2 Application of least absolute shrinkage and selection operator regression analysis for predictor variable selection. A: The least absolute shrinkage and selection operator coefficient trajectory path diagram, where each line represents the coefficient trajectory of an independent variable; B: The cross-validation curve for least absolute shrinkage and selection operator regression analysis, with the dashed line on the left indicating the log (λ) value corresponding to the minimum mean-square error. By selecting log (λ) at the minimum mean-square error, five variables with non-zero coefficients were identified.

Figure 3 Nomogram constructed for predicting post-hepatectomy liver failure. PLT: Platelets; DBIL: Direct bilirubin.

Figure 4 Validation of the nomogram: A: Validation using the area under the receiver operating characteristics curve; B: Calibration curve for verifying the consistency between the predicted probabilities and the actual observed probabilities; C: Decision curve analysis to assess the clinical efficacy of the model. AUC: Area under the receiver operating characteristics curve.