Systematic Reviews
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2016; 8(3): 266-273
Published online Mar 27, 2016. doi: 10.4240/wjgs.v8.i3.266
Fibrin sealant use in pilonidal sinus: Systematic review
Cuneyt Kayaalp, Ismail Ertugrul, Kerem Tolan, Fatih Sumer
Cuneyt Kayaalp, Ismail Ertugrul, Kerem Tolan, Fatih Sumer, Department of Gastrointestinal Surgery, Inonu University, 44280 Malatya, Turkey
Author contributions: Kayaalp C and Ertugrul I designed the research; Kayaalp C and Ertugrul I searched the databanks, analyzed and tabulated the data; Kayaalp C and Sumer F performed the statistical analysis; Kayaalp C, Tolan K and Sumer F wrote the manuscript.
Conflict-of-interest statement: Authors declare no conflict-of-interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at email: Participants gave informed consent for data sharing. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Cuneyt Kayaalp, MD, Professor, Department of Surgery, Turgut Ozal Medical Center, Inonu University, Elazig Cad, 44280 Malatya, Turkey.
Telephone: +90-422-3410660 Fax: +90-422-3410229
Received: August 31, 2015
Peer-review started: September 1, 2015
First decision: September 29, 2015
Revised: December 12, 2015
Accepted: January 5, 2016
Article in press: January 7, 2016
Published online: March 27, 2016
Core Tip

Core tip: Fibrin sealant use in pilonidal disease treatment may involve filling in the sinus tracts, covering the laid-open area after excision, or obliterating the subcutaneous dead space before skin closure. This systematic review demonstrates that when the fibrin sealant was used to obliterate the subcutaneous dead space, there was no reduction in wound complications. It was unadvisable to fill the sinus tracts because it was not superior to the other more cost-effective treatments with a 20% recurrence rate. More studies are necessary for sealant use in covering the laid-open area, which has promising results, predicting shorter wound healing time and increased patient satisfaction.