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World J Gastrointest Surg. Nov 27, 2026; 18(11): 123131
Published online Nov 27, 2026. doi: 10.4240/wjgs.123131
Published online Nov 27, 2026. doi: 10.4240/wjgs.123131
Value of pancreatic duct stent placement combined with octreotide for reducing the postoperative pancreatic fistula rate in patients with diabetes undergoing pancreaticoduodenectomy
Kaisaier Abudouhadier, Department of Emergency Trauma Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830013, Xinjiang Uygur Autonomous Region, China
Jia-Qi Xu, Hai Lin, Department of Pancreatic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830013, Xinjiang Uygur Autonomous Region, China
Author contributions: Abudouhadier K participated in study design, clinical data collection and data analysis, drafted the initial manuscript; Xu JQ conducted data sorting and result interpretation, critically revised the important academic content of the manuscript; Lin H was responsible for the overall design and supervision of the research, performed critical revision of the manuscript; all authors have read and approved the final version of the manuscript; all authors agree to take responsibility for all aspects of the work, and ensure that any issues related to the accuracy or integrity of any part of the study are properly investigated and resolved.
AI contribution statement: Portions of this manuscript were edited using AI tools solely for language refinement. The authors carefully reviewed and verified all AI-assisted outputs and take full responsibility for the scientific content of the manuscript.
Institutional review board statement: The research was reviewed and approved by The First Affiliated Hospital of Xinjiang Medical University
Informed consent statement: All research participants or their legal guardians provided written informed consent prior to study registration.
Conflict-of-interest statement: No conflict of interest is associated with this work.
Data sharing statement: No other data available.
Corresponding author: Hai Lin, Chief, Department of Pancreatic Surgery, The First Affiliated Hospital of Xinjiang Medical University, No. 137 South Liyushan Road, Xinshi District, Urumqi 830013, Xinjiang Uygur Autonomous Region, China. 13639966260@163.com
Received: May 9, 2026
Revised: June 12, 2026
Accepted: June 29, 2026
Published online: November 27, 2026
Processing time: 186 Days and 19 Hours
Revised: June 12, 2026
Accepted: June 29, 2026
Published online: November 27, 2026
Processing time: 186 Days and 19 Hours
Core Tip
Core Tip: This propensity score-matched study in diabetic patients undergoing pancreaticoduodenectomy shows that adding postoperative octreotide to pancreatic duct stent placement significantly reduces clinically relevant postoperative pancreatic fistula (11.7% vs 23.3%), shortens drain retention and hospital stay, and does not affect overall postoperative glucose metabolism. The combined mechanical and pharmacological approach appears safe and beneficial for the type 2 diabetic patients included in this single-center retrospective cohort.