Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 107967
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.107967
Perioperative anticoagulation reduces the incidence of venous thromboembolism in patients undergoing gastrointestinal surgery
Ying Jiang, Jia-Fei Wang
Ying Jiang, Jia-Fei Wang, Department of Gastrointestinal Surgery, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China
Author contributions: Jiang Y participated in the protocol design, data interpretation, data management, and manuscript drafting; Wang JF revised the manuscript, had full access to all of the data analyzed in the study, and was ultimately responsibility for the decision to submit for the article for publication; and all authors thoroughly reviewed and endorsed the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, No. K2024-IRB-059.
Informed consent statement: Due to the retrospective nature of this study, the ethics committee approved a waiver of informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: There are no privacy concerns regarding the data analyzed this study, which can be obtained from the corresponding author upon request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jia-Fei Wang, Department of Gastrointestinal Surgery, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Hangzhou 310000, Zhejiang Province, China. docjf_wang@163.com
Received: April 30, 2025
Revised: May 26, 2025
Accepted: July 9, 2025
Published online: August 27, 2025
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Core Tip

Core Tip: This retrospective study single-center observational study compared the outcomes of perioperative and postoperative venous thromboembolism (VTE) and investigated the risk factors in patients who underwent gastrointestinal surgery. The incidence of VTE peaked within 1 week post-surgery, and prophylactic anticoagulation therapy with low molecular weight heparin reduced the incidence of VTE and exhibited a good safety profile. An age ≥ 65 years, a body mass index ≥ 24 kg/m2, and malignant diseases of the digestive system were identified as risk factors for the occurrence of postoperative VTE in patients undergoing gastrointestinal surgery.